Case
Accelerating Recruitment in a Competitive Phase 2b Trial
How InnoStrat helped a mid-sized pharma client meet enrolment targets and strengthen global KOL relationships
The challenge
Recruiting patients on time while navigating intense market activity, competing trials, and complex protocol requirements.
When a mid-sized pharmaceutical company launched a Phase 2b clinical trial in a highly competitive therapeutic area, they faced a critical challenge: recruiting patients on time while navigating intense market activity, competing trials, and complex protocol requirements.
To meet these demands, the client turned to InnoStrat. Through our Clinical Trial Effectiveness Program, we provided a full-service engagement strategy that drove both performance and partnership. Despite promising data, the client needed to:
- Accelerate patient recruitment in an increasingly saturated trial environment
- Reduce screen failures and maintain high protocol adherence
- Engage and motivate global KOLs and sites across 10 countries
- Lay a solid foundation for a successful Phase 3a program
Our approach
InnoStrat applied its proven Clinical Trial Effectiveness methodology to align stakeholders, empower sites, and turn science into momentum.
Strategic Panel Creation
We established a multi-layered engagement structure including:
- Trial Steering Committee (StC)
- Global Investigator Panel (GIP)
- Global Study Coordinator Panel (GSCP)
These groups acted as advisory boards, driving study insight and ownership from the top down.
A Unified Scientific Narrative
We developed a Trial Core Story – a compelling, clinically relevant narrative derived directly from the protocol. This ensured that all stakeholders shared a common understanding of trial rationale, objectives, and potential impact.
Local Trial Communities
We helped build and support country-level communities led by panel members and facilitated by the client’s MSLs and InnoStrat. These communities fostered site-to-site learning and provided a trusted environment to troubleshoot challenges such as:
- Site onboarding
- Protocol clarifications
- Screen failure reduction
- Retention strategies
Targeted Tools and Communication
Working closely with study teams, we co-created tools and materials designed to support trial success, including:
- Objection handlers and site FAQs
- Investigator training decks
- HCP/patient-facing trial awareness materials
- Customized engagement content for CRAs and MSLs
The result
Our tailored engagement programs strengthened KOL relationships, enhanced protocol adherence, and laid the groundwork for a successful phase 3a program.
Timely Recruitment Achieved
The study met its recruitment milestones across all participating countries—despite an increasingly competitive landscape.
Improved Site Adherence
Site performance and screen failure rates improved thanks to ongoing education, real-time dialogue, and collaborative problem solving.
Global Standardization with Local Relevance
The combination of centralized panels and local trial communities enabled consistent messaging and best-practice sharing while respecting geographic nuances.
Strengthened KOL Relationships
Global panel members expressed high satisfaction with their level of engagement, particularly the enhanced access to the client’s medical leadership.
What this means for you
At InnoStrat, we go beyond recruitment tactics – we create clinical communities grounded in science, trust, and collaboration.
Our Clinical Trial Effectiveness program is proven to deliver measurable impact by aligning stakeholders and energizing trials from within.
